Asma Waheed Qureshi
GC Women University, Pakistan
Title: Anti-fasciolic efficacy of some medicinal plants in comparison with triclabendazole in naturally infected buffaloes
Biography
Biography: Asma Waheed Qureshi
Abstract
The current study Caesalpinia crista (seeds) and Saussurea lappa (roots) were used to treat buffaloes naturally infected with fasciolosis and their efficacy (%) was compared with triclabendazole. A total of 81 (72 infected and 9 normal healthy) buffaloes (Bubalus sp.) of Nili Ravi breed, 6.0�0.1 years of ages and both sexes naturally infested with fasciolosis were used for anthelmintic trails. The infected buffaloes were randomly divided into four main groups??? i.e. C, S, T and I. Animals in groups C and S were further sub divided into three sub groups i.e. C1, C2, C3; S1, S2, S3, each having nine animals. Two more infected groups T and I also have nine infected animals each while group G with nine healthy normal animals. Sub-groups C1 and D1 were given dose level of 50 mg/kg body weight, C2 and D2, 100 mg while C3 and D3, 150 mg/kg body weight of crude Caesalpinia crista (seeds) and Saussurea lappa (roots), respectively. Group T was given triclabendazole (10 mg/kg body weight). While for the comparison of animals in I and G served as infected and healthy control groups, respectively. Efficacy (%) for triclabendazole was 100% after first dose while for the two herbal medicine, after administration of second dose of 150 mg/kg body weight. Anti-fasciolic effects of these plants may be due to the presence of metabolites like alkaloids, tannins, saponins, phenolic compounds and flavonoids. The two plants were found significantly (P<0.05) effective and safe to use against fasciolosis.